There is currently a need to reduce the biocide content of wood preservatives, without decreasing efficacy. The nonmetabolised amino acid analogue α-aminoisobutyric acid (AIB) acts as a translocated inhibitor of mycelial spread in basidiomycete wood decay fungi, although it does not kill the organism. Factorial combinations of AIB with either the azole fungicide tebuconazole, or 3-iodo-2-propynyl butyl carbamate (IPBC), were tested for inhibition of growth in wood decay fungi. The concentration of IPBC required for 95% inhibition of the three fungi tested was reduced by approximately 50% in the presence of 2g/l AIB. AIB did not enhance the inhibitory effect of tebuconazole. Using a the accelerated EN113 test for decay of treated wood blocks, AIB at 1g/l was found to reduce by the concentration of IPBC required for a wood preservative effect.

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