Suitability of propiconazole (R 49362) as a new-generation fungicide

IRG/WP 3529

A R Valcke

Propiconazole (R 49362), an anti-fungal triazole-compound of Janssen Pharmaceutica, has been extensively tested to determine its potential use as a wood preserving fungicide. Various tests in both private laboratories and official institutes indicate a good activity against Basidiomycetes (brown and white rot) and Ascomycetes (blue stain-in-service). The active ingredient seems very resistant to weathering (leaching and evaporation). The compound shows a good lateral penetration into wood. Following mean toxic values (kg a.i./m³ wood) can be given: Coniophora puteana: 0.27-0.39, Gloeophyllum trabeum: 0.37-0.49, Poria placenta: < 0.22 and Coriolus versicolor: 0.25-0.33. Propiconazole does not break down in solventborne and waterborne formulations when exposed to various temperatures. The fungicide is stable in treated wood and can be traced back by using HPLC-or GC-methods. An extensive toxicological and ecotoxicological file has been composed according to OECD and EPA guidelines


Keywords: BLUE STAIN; DECAY; LOSP; PENETRATION; PROPICONAZOLE; CHEMICAL STRUCTURE; CHEMICAL PROPERTIES; DICHLOFLUANID; TBTN; TIMBER IN SERVICE; TRIAZOLE; TOXIC VALUES; WEATHERING

Conference: 89-05-22/26 Lappeenranta, Finland


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