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Glutathione transferases and wood extracts
2015 - IRG/WP 15-10845
Wood rotting fungi have developed an efficient detoxification system allowing them to be well adapted to their way of life, these fungi generating and encountering potential toxic compounds during wood degradation. Belonging to this detoxification network, glutathione transferases are particularly extended in these fungi and their presence could reflect the chemical environments encountered by the...
A Deroy, F Saiag, Z Kebbi-Benkeder, N Touahri, M Morel-Rouhier, F Colin, S Dumarcay, P Gérardin,


Interactions between fungal glutathione transferases and wood extractives
2017 - IRG/WP 17-10894
The interactions between extractives from several tree species of French Guyana and glutathione transferases (GST) from the white-rot Trametes versicolor have been studied. These interactions have been monitored using a thermal shift assay. It appears from these experiments that TvGSTO2S interacts strongly with acetonic extract of Bagassa guianensis and in particular with oxyresveratrol. In agreem...
T Perrot, F Saiag, N Amusant, S Dumarçay, P Gérardin, M Morel-Rouhier, R SormaniI, E Gelhaye


Interactions between wood polyphenols and detoxification enzymes of the white rot Trametes versicolor
2018 - IRG/WP 18-10906
Wood decay fungi have complex detoxification systems that enable them to cope with secondary metabolites produced by plants. Although the number of genes encoding for glutathione transferases (GSTs) is especially expanded in lignolytic fungi, little is known about their physiological target molecules. In this study, by combining thermal shift assay and affinity crystallography we highlighted inter...
M Schwartz, T Perrot, E Aubert, S Dumarçay, F Favier, P Gérardin, M Morel-Rouhier, G Mulliert, F Saiag, C Didierjean, E Gelhaye