Simulation test of subchronic inhalation toxicity of TBTO vapours in the air
IRG/WP 3454
V Skubic, S Kobal, J Stupar, R Ajlec, J Korošin, G R Pecenko
The test was carried out in a wainscotted room of a normal size. Wooden panelling had been treated with one coat of basic preserving agent and, after the installation, with 2 coats of stain. Laboratory animals (rats) were kept in this room for 90 days. For the same period a control group of test animals was kept in a room of equal size where there was no panelling. During the test, concentration of tin (Sn) in the air (originating from TBTO) was measured and the weight of the animals was taken. When the test was completed, typical characteristics of animal tissue likely to be affected by TBTO, were determined. Throughout the test, the quantity of Sn in 1 m³ of air had been approx. 1 µg. No changes i.e. differences in typical parameters of both the test and control animals have been observed (histological tests have not been made yet).