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Connecting fungal genomic variations to wood chemical composition: A way to understand the adaptation of wood decaying fungi
2012 - IRG/WP 12-10776
The development of new sequencing methods allows now exploring the detoxication systems of wood-decaying fungi. These systems, called xenome, are mainly composed of oxidative enzymes (phase I) and of conjugation enzymes (phase II). These enzymes belong to superfamilies, which are extended in the plant cell-wall interacting fungi. From different approaches coupling in particular comparative genomic...
E Gelhaye, Y Mathieu, E Meux, A Thuillier, M Mélanie


Emerging function for a glutathione transferase in response to wood extractives toxicity
2014 - IRG/WP 14-10824
The first steps of wood degradation by fungi lead to the release of toxic compounds known as extractives. To better understand how lignolytic fungi cope with these products, a transcriptomic analysis of Phanerochaete chrysosporium genes was performed in presence of oak acetonic extractives. The most up-regulated genes relate to nutrition, nucleic acid modification, gene regulation, signalling and ...
A Thuillier, K Chibani, A Deroy, S Dumarçay, P Gérardin, A Kohler, J-P Jacquot, E Gelhaye, M Morel-Rouhier